According to the news on the “Clinical Trials Arena” website, Russian drug manufacturer Petrovax started the third stage clinical trials of the vaccine candidate named “Ad5-NCov” in the capital Moscow.
Developed by CanSino in collaboration with the Chinese Military Medical Academy, Ad5-NCov aims to awaken immune responses by transferring the genetic components of Kovid-19 to the human body through a harmless adenovirus component that causes the common cold.
Stage 1 and stage 2 clinical trials, in which the vaccine candidate’s safety and immunity effect were tested, were conducted in China, while stage 3 trials began in Saudi Arabia on August 9. Pakistan approved the stage 3 clinical trials of the vaccine candidate in their country on August 19 and Russia on September 3.
Clinical trials, with a total of 40,000 people planned to participate, are planned to be conducted in Brazil and Chile.
class = “cf”>
The Chinese military approved the vaccine candidate for use as a “special needs health care item” on June 25.
VACCINE STUDIES IN CHINA
In China, where Kovid-19 appeared, clinical trials of 9 vaccine candidates continue. 3 of these are tested on humans in the first stage, 2 in the second stage, and 4 in the third stage.
Public pharmaceutical companies such as Sinopharm, Sinovac and CanSino carry out vaccination studies in cooperation with institutions such as the Chinese Military Medical Academy, Wuhan Virology Institute, Beijing Institute of Biological Products.
Apart from CanSino’s vaccine candidate, “CoronaVac” developed by SinoVac and two vaccine candidates developed by Sinopharm with Vuhan Institute of Virology and Beijing Institute of Biological Products are among the most promising studies.
CLINICAL TRIALS ARE MADE IN 3 STAGES
In order for a vaccine to be widely used, it must be tested on humans in 3 stages.
In the first phase of clinical trials, the safety of the vaccine and possible side effects are investigated in a small number of healthy volunteers. In the second stage, the effectiveness of the vaccine, whose reliability has been confirmed, is tested on more than 100 subjects. In the third and last stage, the same process is repeated with thousands of subjects. This whole process can take months or even years.
38 VACCINE CANDIDATES IN CLINICAL TRIAL
class = “cf”>
According to the data of the World Health Organization (WHO), as of September 21, 38 vaccine candidates against Kovid-19 are in clinical trials and 149 vaccine candidates are at the pre-clinical evaluation stage.
Emerging in China, Kovid-19 spread to more than 200 countries and regions and turned into an epidemic. While the number of cases exceeded 31.5 million worldwide, more than 969 thousand people died.
.
#Hurriyet #Pakistan News Updates
Source link